Other professional guidelines from the Asian-Pacific Association for the Study of the Liver (APASL),5 the American Association for the study of Liver Diseases (AASLD),6 and the European Association for the Study of the Liver (EASL)7 made comparable recommendations for treatment eligibility, although with some differences in thresholds of ALT and HBV DNA for treatment (appendix p 2). The gene discussed is GPT; the disease is liver disorder.