MSLN and neoplasm: When applying indices that could be evaluated preoperatively, univariate analysis using the Cox proportional hazards model revealed that the presurgical serum CEA level (P = 0.017), presurgical serum CA19-9 level (P = 0.049), macroscopic type (P = 0.0076), tumor intestinal annular proportion (P = 0.0049), histological grading (P = 0.034), tumor depth (P = 0.0013), and MSLN expression (P = 0.0028) correlated significantly with the risk of death from CRC recurrence.