HEPHL1 and deafness: Notably, the position of this glycan—which is conserved in many ZP module proteins and whose loss in inner ear α‐tectorin is associated with human deafness (Sagong et al, 2010; Bokhove et al, 2016a)—is stabilized by linker β1 itself, which hydrogen bonds to the amide group of a lactosamine GlcNac via the side chain of R449 (Figs 1G and 3B, right panel; Movie EV1).