An assessment of cell membrane calcium channel proteins in UF tissues showed that the expression patterns of the calcium channel proteins TRPC1 and TRPM7 in UF tissues were different from that in adjacent smooth muscle tissues and the in vitro modification of TRPC1 and TRPM7 expression significantly affected the proliferation of uterine leiomyoma cells [47]. The gene discussed is TRPM7; the disease is Uterine leiomyoma.