F8 and hemophilia: Continuous infusion (CI) is an alternative strategy that avoids FVIII concentration peaks and suboptimal troughs.3The safety and efficacy of CI of FVIII for major surgery has been shown in a variety of studies, including for joint arthroplasties and synovectomies.4, 5, 6, 7, 8, 9Benefits of CI over bolus injection of FVIII products, such as constant factor levels and reduced FVIII consumption, have also been demonstrated in patients with hemophilia in surgical settings.