High levels of these cardiac biomarkers are related to worse prognosis of the disease (19, 20), with a number of studies demonstrating a higher risk of admission to ICU (10), requirement for mechanical ventilation (12), and incidence of arrhythmias and death from COVID-19 (3, 4, 10, 12, 19) in those with elevated circulating hs-cTnI or hs-cTnT levels. This evidence concerns the gene TNNT2 and COVID-19.