In fact, due to this mechanism of entry, there has been debate on the use and potential benefit of the use of ACE inhibitors in patients with cardiac injury and/or hypertension (23), with the American Heart Association, The Heart Failure Society of America, and the American College of Cardiology publishing a joint consensus statement for the treatment of COVID-19 patients with ACE inhibitors (24). This evidence concerns the gene ACE and Hypertension.