Fontana et al. demonstrated transmural LGE to be more prevalent in TTR amyloidosis (63% in TTR amyloid vs. 27% in AL amyloid; p < 0.0001), as opposed to sub-endocardial LGE which appears to be more prevalent in AL amyloidosis (24% in TTR amyloid vs. 39% in AL amyloid; p < 0.05) (15). This evidence concerns the gene TTR and amyloidosis.