Wightman et al. reported that the CXCL10/CXCR3 axis might be responsible for the metastasis of melanoma cells to the lungs and CXCL10/CXCR3 co-expression in melanoma as well as colon and renal cancers are associated with increased metastatic competence (Wightman et al., 2015). This evidence concerns the gene CXCR3 and renal carcinoma.