IGHE and dermatitis herpetiformis: These hypersensitivities commonly referred to as wheat-related disorders (WRDs) can be classified into CD, gluten ataxia, and dermatitis herpetiformis characterized by an autoimmunogenic response (IgA and IgG antibodies), into IgE- and non-IgE-mediated WA and into NCGS characterized by an innate immune response (78) (Figure 2).