MTOR and infection: • Use of multiple antimicrobial agents • Change in gut microbial composition from viral proinflammatory mediators (14) • Abnormal mTOR activity and decreased antimicrobial activity (15) • Increased susceptibility for infections (Clostridium difficile) (16) • Hypochlorhydria induced by antisecretory agents (such as the use of proton pump inhibitors) (17) • Altered gut-lung axis (18)