Ras-association domain family 1A (RASSF1A) is a recently discovered tumor suppressor whose inactivation is implicated in development of many human cancers (Dammann et al., 2000; Burbee et al., 2001; Chan et al., 2003; Pan et al., 2005; Pfeifer and Dammann, 2005). This evidence concerns the gene RASSF1 and cancer.