Among various fibrotic diseases, CTGF has been extensively studied in pulmonary fibrosis (Allen and Spiteri, 2002), Cardiac fibrosis (Dorn et al., 2018), liver fibrosis (Gressner and Gressner, 2008), renal fibrosis (Toda et al., 2018), Duchenne muscular dystrophy (DMD) (Morales et al., 2011), and ocular disorders (Kubota and Takigawa, 2015). The gene discussed is CCN2; the disease is Duchenne muscular dystrophy.