Given that two clinically used PDE inhibitors cilostazol and milrinone have been shown to suppress the hypothermia-induced ventricular tachycardia/ventricular fibrillation by reversing the repolarization abnormalities (Gurabi et al., 2014), we tested their effects on our iPSC-CMs at therapeutically relevant concentrations (Szel et al., 2013). The gene discussed is ALDH7A1; the disease is ventricular tachycardia.