PPARA and ulcerative colitis: Ulcerative colitis is usually accompanied by the accumulation of colon stem cells and undifferentiated transit expanded cells at the base of the crypt (Papapietro et al., 2013), resulting in the inhibition of peroxisome proliferator-activated receptor (PPAR) synthesis in epithelial cells (Dubuquoy et al., 2003; Litvak et al., 2018).