Also, a cell cycle inhibitor (Tachon et al., 2018), a dopamine receptor antagonist (Dolma et al., 2016), an adrenergic receptor antagonist (He et al., 2017), a VEGFR inhibitor (Kalpathy-Cramer et al., 2017), a PPAR receptor agonist (Im, 2016; Gupta et al., 2018), a PI3K inhibitor (Zhao et al., 2017), mTOR inhibitors (Friedman et al., 2013), a lipoxygenase inhibitor (Zappavigna et al., 2016), and an HMGCR inhibitor (Hamm et al., 2014) have been shown to exhibit anticancer effects on GBM cells, some of which have been shown to target GSCs. This evidence concerns the gene KDR and glioblastoma.