WWOX and neoplasm: In coincidence with its tumor suppressor function, overexpression of WWOX protein in malignant lung, breast, pancreatic, cervical, and prostate cancer cells suppresses cell growth and increases cell apoptosis (Fabbri et al., 2005; Iliopoulos et al., 2007; Nakayama et al., 2008; Qu et al., 2013; Lin et al., 2015).