BSG and cancer: Previous studies revealed that high CD147 expression on cancer cells is linked to CSC characteristics, such as EMT, anoikis-resistance, and chemoresistance (Ma et al., 2010; Wu et al., 2011; Ke et al., 2012; Dai et al., 2013), indicating that cancer cells expression high levels of CD147 could be more aggressive and prone to cancer metastasis and recurrence.