The pharmacologic inhibition or knockout of LAT1 can inhibit the growth and mTOR signaling pathways of various tumor cell lines, such as human colon adenocarcinoma cells (LS174T and HT29), lung cancer cells (A549 and H1975), and renal carcinoma cells (786-O and A498) (Oda et al., 2010; Cormerais et al., 2016; Salisbury and Arthur, 2018). The gene discussed is LAT; the disease is neoplasm.