These effects indicate that LAT1 is necessary for the action of mammalian target of rapamycin complex 1 (mTORC1) and the mediation of islet β-cell signal and function; LAT1 may also be a new drug target for the therapy and prevention of type 2 diabetes (T2D) (Cheng et al., 2016). The gene discussed is SLC7A5; the disease is type 2 diabetes mellitus.