RELA and infection: In contrast with the concurrent increase of RELA (p65), NFKB1 p50 and IκBα in the nuclei of activated or infected HL-60 cells and evidence that the canonical NF-κB pathway is active, is the increased detection of a NF-κB2 protein in infected vs. uninfected HL-60 cell nuclei as long as 7 days after infection, and increases in NFKB2 transcription among transcriptional profiling studies (Supplementary Table 1C).