Lastly, some authors suggest that HLA-DRB1*1501 and HLA-DRB1*1503 confer the highest risk of developing ABPA, whereas HLA-DQ2 (HLA-DQB1*0201 in particular) provides relative protection against the development of ABPA (18–20). The gene discussed is HLA-DRB1; the disease is allergic bronchopulmonary aspergillosis.