by different TLRs (Becker et al., 2003; de Veer et al., 2003) and an important correlation in the protective responses against Leishmania parasites with high expression of TLR-2, -4, and -9 in parasite infections were identified (Martínez-Salazar et al., 2008; Faria et al., 2012). The gene discussed is TLR2; the disease is infection.