So far, the researchers mainly clarified that the enzymes related to fatty acid synthesis (FASN, ACC, ACLY, SCD) and lipid degradation related enzymes (MAGL, CPT, 5-LO, COX2), and receptors related to lipid uptake (FABP4, CD36, LDLR) play important roles in promoting cancer development (Figure 1). This evidence concerns the gene ACLY and cancer.