ZEB2 and breast carcinoma: Most of these lncRNAs have not yet been functionally characterized; however, lncRNA ZEB2-AS, a lncRNA involved in the regulation of the transcription factor ZEB2 during epithelial-mesenchymal transition (EMT) in human colon, pancreatic, and breast cancer cell lines (159), was highly expressed in canine oral melanomas compared to control samples.