The prevalence of BRCA1/2 mutations in the current cohort of TNBC cases reached 24.1%, which was close to the reported rate of 21.4% in unselected Chinese populations (50), indicating that BRCA1/2 mutations were not related to high tumor burden or worse prognosis, in agreement with the findings of the POSH study (16). Here, BRCA1 is linked to neoplasm.