KRAS is the most commonly mutated oncogene in non-small cell lung cancer (NSCLC), occurring mainly in lung adenocarcinomas (30%) and less frequently in squamous cell carcinoma (5%) (2, 3) Treatments directed toward KRAS mutations are not available because of limited efficacy resulting from failure to inhibit the protein directly, or inhibit its downstream effectors (4). This evidence concerns the gene KRAS and lung adenocarcinoma.