In the same line, gene expression analysis reported that patients with upregulation of six of these hub genes (genes with high correlation in candidate modules) (ACACB, acyl-CoA dehydrogenase medium chain, adiponectin, C1Q and collagen domain containing, acyl-CoA synthetase short-chain family member 2, phosphoenolpyruvate carboxykinase 1 and PLIN1) displayed improved breast cancer prognosis (106). This evidence concerns the gene PLIN1 and breast carcinoma.