EZH2 and melanoma: Mir-137 can inhibit the migration and invasion of melanoma cells 45–47 by targeting various mRNAs such as PIK3R3, TBX3, c-Met, YB1, EZH2, and MITF (47–49), and inhibit the proliferation and promote the apoptosis of melanoma cells by competitive binding to genes such as SLC1A5, GLO1, CDK6, etc. (50–52).