The four hub mRNAs (FKBP4, RCC1, GBP1, and PRADC1), one miRNA (hsa-mir-137), and seven lncRNAs (HCP5, SNHG14, FGD5-AS1, HCG18, MAGI2-AS3, OIP5-AS1, and TUG1) in ceRNA network play important roles in the development of melanoma and other various tumors and are widely involved in the immune regulation process. This evidence concerns the gene FGD5 and melanoma.