In the immunohistochemical analysis of specimens from gastric cancer, lung adenocarcinoma, primary OSCC, prostate cancer, and esophageal cancer, CNTN1 expression was significantly positively associated with lymphatic invasion, metastasis, late TNM stage, and a short overall survival time (9, 12, 13, 16, 18, 22–25). The gene discussed is CNTN1; the disease is prostate cancer.