The mRNA expressions of ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1C1, ATP6V1D, ATP6V1E1, ATP6V1G1, ATP6V1G2, ATP6V1G3, and ATP6V1H were remarkably correlated with cancer stages, while mRNA expressions of ATP6V1A, ATP6V1B1, ATP6V1D, ATP6V1G2, and ATP6V1G3 were significantly related to nodal metastasis status. The gene discussed is ATP6V1D; the disease is cancer.