CD80 and ovarian carcinoma: Hyaluronic acid-based nanoparticles encapsulating miR-125b (HA-PEI-miR-125b) specifically target TAMs in the peritoneal cavity of a syngeneic ID8-VEGF ovarian cancer mouse model and repolarize macrophages to an immune-activating phenotype (increased CD80 and iNOS and reduced CD206 and ARG1 expression) (237).