MRC1 and neoplasm: RNA-seq analysis also revealed that CD163+ or CD206+ TAMs isolated from the ascites of HGSOC patients (Germany cohort) have elevated expression of protumorigenic growth factors and cytokines, e.g. CCL18, KITLG, SEMA6B, S100B, and VEGFB and downregulated tumor suppressive mediators, e.g. CXCL10, CXCL11, IL15, TNFSF10, and TNFSF14 (226).