Regardless of the fact that unirradiated tumors grown on CD39−/− and CD73−/− mice already had higher percentages of tumor-infiltrating leukocytes, our flow cytometry data revealed that exposure to a single high-dose irradiation did not significantly increase the percentage of leukocytes and respective subsets infiltrating LLC1 tumors grown on CD39−/− mice after irradiation. This evidence concerns the gene ENTPD1 and neoplasm.