Characterization of purinergic signaling in the tumor cells revealed that LLC1 cells uncovered a CD39 gene expression that was not altered by irradiation (data not shown), but cell surface staining revealed that the LLC1 cells did neither express CD39, CD73, nor the ATP receptor P2X7R (Figure 1B), nor did irradiation with 5 or 10 Gy induce an expression of these markers (data not shown). Here, ENTPD1 is linked to neoplasm.