NT5E and neoplasm: As expected, exposure to a single dose of 10 Gy induced a significant growth delay of the LLC1 tumors in the irradiated C57BL/6, as well as in the irradiated CD73−/− mice, compared to their unirradiated controls resulting in a difference in tumor volume of 180.2 ± 47.75 mm3 in WT and 210.2 ± 47.63 mm3 in CD73−/− mice at day 9 after irradiation (Figures 2A,B).