The univariate Cox regression model revealed that age at diagnosis (HR = 1.03, 95% CI = 1.02 to 1.05, P < 0.001), pathological stage (HR = 1.71, 95% CI = 1.41 to 2.08, P < 0.001), and POLR3G expression (HR = 1.04, 95% CI = 1.01 to 1.07, P = 0.02) were associated with overall survival of patients with TCC. The gene discussed is POLR3G; the disease is tarsal-carpal coalition syndrome.