POLR3G and tarsal-carpal coalition syndrome: RNA-Seq differential expression analysis revealed that 2,211 genes were up-regulated (log2FC > 1, and FDR < 0.01) in TCC tissues compared to normal bladder tissues, including POLR3G (log2FC = 1.038, FDR = 0.006), and 1,853 genes were down-regulated (log2FC <-1, and FDR <0.01).