The other proteins in these pathways were members of the families of interleukin (ITGA2, ITGB6), laminin (LAMC2), and collagen (COL1A1/2, COL6A3), together with cartilage oligomeric matrix protein (COMP), whose role in pancreatic cancer has not yet been clarified. This evidence concerns the gene COL1A1 and familial pancreatic carcinoma.