The incidences of AKI in the CRP/albumin ratio ≥ 0.1 group were significantly higher than those in the CRP/albumin ratio < 0.1 group in the unadjusted (OR = 3.905, 95% CI = 2.423–6.294, P < 0.001), multivariate-adjusted (OR = 3.591, 95% CI = 2.142–6.020, P < 0.001), and propensity score-matched cohorts (OR = 4.111, 95% CI = 1.984–8.518, P < 0.001) (Figure 4). The gene discussed is CRP; the disease is acute kidney injury.