KDR and nasopharyngeal carcinoma: As VEGFR2 is the main receptor of VEGF signalling and autocrine VEGF-VEGFR2 signalling stimulates the secretion of VEGF in diverse cell types 11, 16-18, we treated NPC cells with rhVEGF (30 ng/ml) for 0, 15, and 30 min to examine the effects of the VEGF-VEGFR2 signalling pathway on EMT and MMPs.