The AUC of VCA-IgA in diagnosis of NPC by CLIA, ELISA-1 and ELISA-2 were 0.929 (95% CI: 0.905-0.953), 0.814 (95% CI: 0.774-0.854) and 0.906 (95% CI: 0.879-0.933), respectively. The gene discussed is CD79A; the disease is nasopharyngeal carcinoma.