The results revealed several predictors of HCC diagnosis, namely tumor size > 12.45 mm, age > 56.61 years, liver cirrhosis, presence of HCV, ln(AFP) > 1.954, arterial phase enhancement in CE CT or CE MR images, and portal or venous phase washout appearance without arterial phase enhancement in CE CT or CE MR images (Table 2); their estimated odds ratios (ORs) and 95% confidence intervals (CIs) were 2.0735 (1.4746-2.9155), 1.8878 (1.2949-2.7521), 1.6927 (1.1294-2.5369), 1.6186 (1.0347-2.5321), 2.0297 (1.3342-3.0876), 3.7451 (2.3845-5.8821), and 2.0327 (1.3500-3.0608), respectively. The gene discussed is AFP; the disease is hepatocellular carcinoma.