For the ICGC-HCC dataset, as shown in Supplementary Figure S2, six kinds of immune cells including CD4+ naive, Tfh, MAIT, monocyte, NK cell, and CD4+ T cell were shown to be significantly negatively correlated (R < −0.15 and p < 0.01), while DC and B-cell infiltrations were positively correlated (R > 0.15 and p < 0.05) with KPNA2 expression in HCC tumors. The gene discussed is CD4; the disease is hepatocellular carcinoma.