Interestingly, the significant correlations of AUH (Supplementary Figure S3A), SF3B4 (Supplementary Figure S3C), DDX3X (Supplementary Figure S3E), PUM2 (Supplementary Figure S3G), and TARDBP (Supplementary Figure S3H) with MKI67 were only shown in the HCC tumors, while not in their paired normal liver tissues (p > 0.05), indicating the specific associations with HCC progression. Here, PUM2 is linked to hepatocellular carcinoma.