In recent years, The dysregulation and/or prognostic roles of KPNA2 were reported in many tumors including esophageal squamous cell carcinoma (Song et al., 2019), breast cancer (Groheux et al., 2018; Wang et al., 2019a), myeloma (Kriegsmann et al., 2019; Tachita et al., 2020), clear cell renal cell carcinoma (Müller et al., 2019), oral cancer (Wang et al., 2018), bladder cancer (Jeong et al., 2017), and colorectal cancer (Ostasiewicz et al., 2016; Jeong et al., 2017). The gene discussed is KPNA2; the disease is colorectal cancer.