KPNA2 and hepatocellular carcinoma: At protein level, through CPTAC-HCC analysis, KPNA2 (p < 0.001; Figure 6A) and GRB2 (p < 0.001; Figure 6B) were found to be higher expressed in HCC tumors than their normal liver tissues, consistent with their upregulation in HCC tumors at mRNA level.