Further, multiple RBPs can regulate the androgen receptor (AR) pathway to influence PCa neoplasia and progression; for instance, HNRNPL is aberrantly expressed in PCa and regulates the alternative splicing of many types of RNA, including those encoding the AR, to influence the progression of PCa (Fei et al., 2017). The gene discussed is HNRNPL; the disease is posterior cortical atrophy.