GFI1 and T-cell non-Hodgkin lymphoma: The Gfi1 gene was first identified almost three decades ago in a screen for Moloney murine leukemia virus (Mo-MuLV) insertions as a factor promoting IL-2-independent growth in a mouse T cell lymphoma cell line (Gilks et al., 1993), whereas GFI1B was identified a few years later in human through a homology screening using low-stringency hybridization with the chick and the mouse GFI1 zinc finger coding sequence (Rodel et al., 1998; Tong et al., 1998).