GFI1 and cerebellar ataxia: Indeed, it has been shown that GFI1 for instance plays a critical role in the biogenesis of hair cells of the inner ear and that a loss of GFI1 leads to deafness and ataxia in mice (Wallis et al., 2003; Hertzano et al., 2004, and reviewed in Costa et al., 2017; Zhong et al., 2019).