TMPRSS11D and metabolic dysfunction-associated steatotic liver disease: Conversely, inhibition of HAT activity prevents NAFLD: the novel HAT inhibitor, tannic acid, binds to p300 and disrupts its occupancy on lipogenic genes (e.g., Fasn, Acly), leading to hypoacetylation of H3K9ac and H3K36ac (Chung et al., 2019).