RNA-binding motif protein 10 (RBM10) is a regulator of alternative splicing in lung adenocarcinoma (Hernandez et al., 2016); and human antigen R (HuR) promotes cell dedifferentiation and proliferation by regulating the stability of target mRNAs in hepatocellular carcinoma (Fernandez-Ramos and Martinez-Chantar, 2015). Here, RBM10 is linked to hepatocellular carcinoma.