CD4 and gastric cancer: Meanwhile, by investigating a correlation between these three genes and immune cells in gastric cancer patients based on the TIMER website, we found that the expression of NOX4, COL8A1, and CHST1 was positively correlated with the degree of infiltration of CD8+ T cells, CD4+ T cells, macrophages, neutrophils, and dendritic cells in the immune microenvironment (P < 0.05) (Figure 12).