1089C>A), 25 (MSH2, c.2168C>T), 29 (PMS2, c.736_741delinsTGTGTGTGAAG), 36 (PMS2, c.2275+1G>C) and 24 (RPS20, c.98A>T) compared to an average age of 40.5 years of the youngest person diagnosed with CRC in the rest of the participant’s families (only 1st to 3rd degree relatives are included). This evidence concerns the gene PMS2 and colorectal carcinoma.