Intragenic-DMGs at 0.8% CO2 vs. 0.4% and 0.1% included: PDLIM7, whose resulting protein regulates valve annulus size and hemostasis (Krcmery et al., 2013); TGFB1, which regulates postnatal cardiomyocyte differentiation (Engelmann et al., 1992); and ILK, which has been shown to exhibit protective effects against cardiomyopathy (Hannigan et al., 2007). This evidence concerns the gene ILK and cardiomyopathy.