Nuclear paraspeckle assembly transcript 1 modulates DNA-damage response in cancer cells, and its upregulation was strongly correlated with poor prognosis and negative clinical–pathological parameters such as the numbers of tumor nodes, metastasis, tumor–node–metastasis (TNM) stage, and cell migration and invasion in different tumors (Guo et al., 2015; Ghafouri-Fard and Taheri, 2019). The gene discussed is NEAT1; the disease is cancer.