Cell lines used were two neuronal cancer cell lines (neuroblastoma LAN-1-p53–/– and glioblastoma T98G with mutant p53), two cancer intestinal cell lines (colorectal carcinoma HCT116 cells with p53+/+ and colorectal carcinoma HCT116 cells-p53–/–) and the human liver cancer cell line HepG2 with p53+/+. Here, TP53 is linked to colorectal carcinoma.