Moreover, a comprehensive prognostic signature were generated by integrated analysis of all the seven types of AS events (abbreviated as “ALL”), which consist of 12 AS events (MTMR10-29790-AA, SLC20A2-83730-AP, NUDT9-69869-AD, FDXR-43316-ES, DLK1-93561-RI, OXNAD1-63641-AA, KANK1-85709-AP, NFKB2-12948-AA, DTNA-45096-AT, ACHE-81032-ES, ZBTB47-64310-RI and ELP3-83203-ES) (Figure 3H). The gene discussed is FDXR; the disease is acute lymphoblastic leukemia.