KEGG pathway analysis showed that lncRNA EPB41L4A-AS1 was mainly involved in four pathways, including RNA transport, MAPK signaling pathway, transcriptional misregulation in cancer, and TNF signaling pathway, suggesting that lncRNA EPB41L4A-AS1 may function as a regulator in the metabolism of NSCLC. This evidence concerns the gene TNF and non-small cell lung carcinoma.