AKT1 and non-small cell lung carcinoma: Jiang et al. found that hydroxysafflor yellow A (HYSA) can reduce LPS-mediated proliferation, migration, invasion and epithelial-mesenchymal transition (EMT) in non-small cell lung cancer (NSCLC) cells by inhibiting PI3K/AKT/mTOR and ERK/MAPK signaling pathways (Jiang et al., 2019).