In order to determine the frequency of these predisposing mutations in solitary schwannomas, Pathmanaban et al. screened 135 schwannoma cases using Sanger sequencing or next-generation sequencing, and the results showed that NF2, LZTR1, or SMARCB1 mutations were found in 54.5% of them (Pathmanaban et al., 2017). The gene discussed is NF2; the disease is schwannoma.