DNAJC7 and amyotrophic lateral sclerosis: Recently, Farhan et al. (2019) identified DNAJC7, a novel gene implicated in ALS, in a large, case-control, whole-exome sequencing (WES) study, in which they observed six distinct protein-truncating variants (PTVs) in eight individuals among 5,095 cases and none in 28,910 controls.